A month later, it received approval for the test kit to be used at home. Today’s addition of puzzles, “just felt like the right time,” Eric von Coelln, executive director of puzzles, said by email. “This virus has a lot of evasion mechanisms.”. It’s not just the lungs — the pathogen may enter brain cells, causing symptoms like delirium and confusion, scientists reported. That can be particularly alluring right now. “When sports leagues started calling us,” Feldman said, “they said almost universally, ‘We have athletes who want to come back to practice and we need a plan that could safely bring them back.’”. Spectrum, based outside Salt Lake City, teamed up with a laboratory at Rutgers University, made a few tweaks and found that the effectiveness of their saliva test kit was comparable to the nasopharyngeal test, or the long swab, that was already in widespread use. Her team then looked at two sets of mice — one with the ACE2 receptor expressed only in the brain, and the other with the receptor only in the lungs. Phillips, the Spectrum Solutions executive, said that he had talked with nearly all of the professional sports leagues in the U.S., including the National Women’s Soccer League and U.F.C., because many compare notes. Saturday’s paper will feature a Wit Twister, a puzzle in the form of a verse. Follow the @ReaderCenter on Twitter for more coverage highlighting your perspectives and experiences and for insight into how we work. The virus may get to the brain through the olfactory bulb — which regulates smell — through the eyes or even from the bloodstream. The coronavirus is much stealthier: It exploits the brain cells’ machinery to multiply, but doesn’t destroy them. The coronavirus seems to rapidly decrease the number of synapses, the connections between neurons. Thanks to automation, Dr. Andy Brooks, the chief operating officer of RUCDR, said his lab in Piscataway, N.J., could handle 50,000 tests per day, with more room to grow. Immune cells then flood the damaged sites, trying to cleanse the brain by destroying infected cells. On Mondays, Wednesdays and Fridays, you’ll find a tweet-sized riddle called Brain Tickler. Dr. Daniel Eichner, the president and laboratory director of SMRTL, the shorthand name for the Utah lab doing M.L.B.’s coronavirus testing, acknowledged that there was “nothing good about this virus.” But, he said, he was proud of his team’s ability to pivot to this new challenge, like other companies. Levinson, the tour executive, said the saliva test was basically used to approve travel: Golfers and caddies take the test before heading to an event, and then once again on the Saturday of a tournament to determine if they can board the tour’s charter plane on Monday to the next event. “They make you feel better. “We call it the brain tickler,” said Jason Feldman, the chief executive of Vault Health. No matter age or skill level, Mr. Shortz, 67, who has made puzzles since he was 8 and received a self-designed undergraduate degree in enigmatology, or the scientific study of puzzles, promised something for everyone and said he hoped that readers would find at least one game addictive. Click the clue to reveal the correct answer … Continue reading New York Crossword Answers June 1, 2020 And two games of the spatial-reasoning exercise Two Not Touch will appear every day but Sunday. Mr. Shortz will create the Brain Tickler and will be joined by a new set of puzzle makers who share his passion. Monday to … The PGA Tour, which had restarted competition in mid-June in Texas, was the first professional sports organization to hire Vault, Feldman said. Some develop serious neurological complications, including nerve damage, scientists have found. He hoped to double that number, and his staff, to about 500, by August. The researchers didn’t find any evidence of an immune response to remedy this problem. It’s unclear which route the pathogen is taking, and whether it does so often enough to explain the symptoms seen in people. But M.L.B.’s testing got off to an uneven start as teams began formal training again this month. When leagues began exploring their options — Levinson said the tour consulted laboratory directors and its own medical advisers — saliva-based tests emerged as a popular choice. “We call it the brain tickler,” said Jason Feldman, the chief executive of Vault Health. In early March, as the coronavirus was spreading across the United States and testing capacity was already a problem, Bill Phillips had an idea. “It’s quite possible that you’ll see a combination of both.”. The virus infects a cell via a protein on its surface called ACE2. In the wake of those hiccups, an M.L.B. A new study offers the first clear evidence that, in some people, the coronavirus invades brain cells, hijacking them to make copies of itself. A handful of companies and labs quickly overhauled themselves to fulfill the sudden demand for coronavirus testing from the major American pro leagues. They have had to weigh the efficacy and speed of various tests and companies, all while trying to ensure they would not be taking away resources from those who needed them more.
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